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Three-dimensional mapping of differential amino acids of human, murine, canine and equine TLR4/MD-2 receptor complexes conferring endotoxic activation by lipid A, antagonism by Eritoran and species-dependent activities of lipid IVa in the mammalian LPS sensor system

机译：人类，鼠类，犬类和马类TLR4 / MD-2受体复合物的不同氨基酸的三维映射，可在哺乳动物LPS传感器系统中赋予脂质A内毒素激活，埃瑞托兰拮抗作用以及脂质IVa的物种依赖性活性

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Julian A. Yunes-Rojas; Vianihuini Figueroa-Vazquez; Jorge Lozano-Aponte; Thomas Scior; Ulrich Zähringer; Christian Alexander;
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1. THREE-DIMENSIONAL {MAPPING} {OF} {DIFFERENTIAL} {AMINO} {ACIDS} {OF} HUMAN, MURINE, {CANINE} {AND} {EQUINE} TLR4/MD-2 {RECEPTOR} {COMPLEXES} {CONFERRING} {ENDOTOXIC} {ACTIVATION} {BY} {LIPID} A, {ANTAGONISM} {BY} {ERITORAN} {AND} SPECIES-DEPENDENT {ACTIVI [J] . Thomas Scior, Jorge Lozano-Aponte, Vianihuini Figueroa-Vazquez, Computational and Structural Biotechnology Journal . 2013,第9期

机译：三维{映射} {OF} {差异} {AMINO} {酸} {OF}人，鼠，{犬} {和} {马匹} TLR4 / MD-2 {受体} {复合物} {授予} {内毒素} {ACTIVATION} {BY} {LIPID} A，{ANTAGONISM} {BY} {ERITORAN} {and}与种类有关{ACTIVI
2. {REVIEWING} {AND} {IDENTIFYING} {AMINO} {ACIDS} {OF} HUMAN, MURINE, {CANINE} {AND} {EQUINE} {TLR4} / MD-2 {RECEPTOR} {COMPLEXES} {CONFERRING} {ENDOTOXIC} {INNATE} {IMMUNITY} {ACTIVATION} {BY} LPS/LIPID A, {OR} {ANTAGONISTIC} {EFFECTS} {BY} ERITORAN, {IN} [J] . Thomas Scior, Christian Alexander, Ulrich Zaehringer Computational and Structural Biotechnology Journal . 2013,第6期

机译：{评论} {并且} {识别} {酰胺} {酸} {OF}人，鼠，{犬} {和} {马匹} {TLR4} / MD-2 {接收者} {复合物} {授予} {内毒素} {INNATE} {IMMUNITY} {ACTIVATION} {BY} LPS / LipID A，{OR} {ANTAGONISTIC} {效果} {BY} ERITORAN，{IN}
3. Anti-endotoxic activity and structural basis for human MD-2 center dot TLR4 antagonism of tetraacylated lipid A mimetics based on beta GlcN(1 <-> 1)alpha GlcN scaffold [J] . Garate Jose Antonio, Stoecki Johannes, del Carmen Fernandez-Alonso Maria, Innate immunity . 2015,第5期

机译：基于βGlcN（1-> 1）alpha GlcN支架的四酰化脂质A模拟物对人MD-2中心点TLR4拮抗作用的抗内毒素活性和结构基础
4. Three-dimensional mapping of differential amino acids of human murine canine and equine TLR4/MD-2 receptor complexes conferring endotoxic activation by lipid A antagonism by Eritoran and species-dependent activities of Lipid IVA in the mammalian LPS sensor system [O] . Thomas Scior, Jorge Lozano-Aponte, Vianihuini Figueroa-Vazquez, 2013

机译：人类鼠类犬类和马类TLR4 / MD-2受体复合物的不同氨基酸的三维映射可在脂质体IVA传感器系统中通过脂质A内毒素激活依立托仑拮抗作用和脂质IVA的物种依赖性活性
5. THREE-DIMENSIONAL MAPPING OF DIFFERENTIAL AMINO ACIDS OF HUMAN, MURINE, CANINE AND EQUINE TLR4/MD-2 RECEPTOR COMPLEXES CONFERRING ENDOTOXIC ACTIVATION BY LIPID A, ANTAGONISM BY ERITORAN AND SPECIES-DEPENDENT ACTIVITIES OF LIPID IVA IN THE MAMMALIAN LPS SENSOR SYSTEM [O] . Thomas Scior, Jorge Lozano-Aponte, Vianihuini Figueroa-Vazquez, 2013

机译：人，小鼠，犬和咪唑TLR4 / mD-2复合接收器的差异氨基酸三维映射脂质a引起的内毒素激活

Three-dimensional mapping of differential amino acids of human, murine, canine and equine TLR4/MD-2 receptor complexes conferring endotoxic activation by lipid A, antagonism by Eritoran and species-dependent activities of lipid IVa in the mammalian LPS sensor system

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